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Aug 31 (Reuters) – Drugmakers have begun shipping copycat versions of Takeda Pharmaceutical’s drug Vyvanse, which is expected to offset the ongoing shortage of the ADHD medicine in the United States.

The U.S. Food and Drug Administration had said on Monday it has approved generic versions of Vyvanse from 11 drugmakers after Takeda’s exclusivity over the drug expired on Aug. 24. Copycats of the drug come in capsules and chewable tablets, ranging between 10 milligrams to 70 milligram doses.

U.S.-based drugmakers Mallinckrodt and Viatris , UK-based Hikma Pharmaceuticals and Indian drugmaker Sun Pharmaceutical Industries confirmed on Thursday they began shipping their generic versions of the drug, which is also approved for a binge-eating disorder in adults.

The generic drugmakers said they are working with the Drug Enforcement Administration (DEA) as the drugs are classified as a controlled substance.

Controlled substances are medications that can cause physical and mental dependence, and have restrictions on how the prescriptions can be refilled.

“We will be working closely with the DEA to request and secure additional quota to increase our production following this approval,” Mallinckrodt said.

Since October, the FDA has warned of an ongoing shortage of Teva Pharmaceutical Industries Ltd’s Adderall, after the Israel-based drugmaker had flagged intermittent manufacturing delays.

That shortage led to a jump in demand for Vyvanse, which combined with manufacturing issues, has resulted in a shortage of Takeda’s drug.

(Reporting by Sriparna Roy in Bengaluru; Editing by Krishna Chandra Eluri)

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ADDERALL Alternatives While Pregnant

Taking a common drug used to treat ADHD may improve the test scores of students, new research suggests.

Adderall, growing popular as a so-called ‘smart drug’, helped to boost memory and attention in a small trial.

But researchers said it works only as a placebo effect – and believing anything may help could trigger similar results. 

Adderall, growing popular as a so-called ‘smart drug’, helped to boost memory and attention in a small trial, researchers said

University of Alabama, Birmingham, scientists were behind the findings, reported in New Scientist. 

How was the study carried out? 

Some 32 participants were involved in the study, which was published in the journal Alcohol and Drug Dependence. 

All were aged between 19 and 30 and didn’t have ADHD. They took a series of cognitive tests four times. 

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In two of the trials they were given 10mg of Adderall – known to be addictive and, in rare cases, can cause death by jump-starting the cardiovascular system.

A placebo was used in the other experiments, the researchers said.

To test the placebo effect, in each of the two trials for the treatments, they were told one was a real medication and the other a placebo. 

What did they find? 

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