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The breakthrough drug Ozempic that has helped over 50 million Americans lose weight has also helped smokers and problem drinkers curb their cravings.

A smattering of trials involving rats and humans, as well as a growing number of anecdotal reports, have shown that Americans prescribed semaglutide – the active ingredient in the diabetes drug Ozempic – saw their alcohol and nicotine use gradually drop off.

The drug has also been shown to help its millions of users curb other compulsive behaviors besides drug and alcohol use, from the seemingly innocuous like nail biting and binging sweets to potentially ruinous impulsive spending and gambling.

Scientists believe that the drug does more than just regulate blood sugar and make you feel satisfied quicker when eating. It can control the brain’s complex reward pathway that floods the brain with a rush of dopamine when something good happens, such as biting into a delicious cookie, and encourages you to eat more.

The potential use of the injectable weight loss aids for addictive behaviors would change the landscape of treatment, which is often limited to just a handful of government-approved medications that fail to prevent relapses long-term.

Henry Webb, from North Carolina, finished a two-month course of Wegovy after hitting his weight goal. In the past, he would consistently have a couple of drinks in the evening, but said: ‘On the medication I had zero desire for that’

Staci Rice (pictured), 40, said that she can no longer stomach coffee or Kit-Kats after using Wegovy

In 2022, more than 5 million prescriptions for Ozempic, Mounjaro, Rybelsus, or Wegovy were written for weight management, compared with just over 230,000 in 2019. This marks an increase of more than 2,000 percent, according to market research firm Komodo Health

Dr Chris Palmer, a Harvard psychiatrist who focuses on the connection between mental health and metabolism told DailyMail.com: ‘The exact same brain circuits that are regulating our food intake are also playing a role in our addictive behaviors.’

Medications like Ozempic and Wegovy that help people shed excess pounds are called GLP-1 agonists, which mimic the GLP-1 hormone naturally produced by the gut in response to eating.

This hormone curbs hunger and slows the the rate at which a person’s stomach empties, leaving them feeling fuller for longer. GLP-1 agonists might also decrease the brain’s response to rewarding stimuli, including delicious food and potentially other substances like alcohol and nicotine.

Dr Palmer added: ‘The general rule of thumb is substances that promote our survival and or ability to reproduce, trigger that [dopamine reward] system. Addictive substances trigger that system and in a way it becomes circular logic.

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